大麻消费者的大动脉动脉瘤和剖析的开放修复后的结果大麻消费者
Lucas Ribé Bernal1, Akiko Tanaka1, Yuki Ikeno1
1Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at UTHealth Houston, Houston, Tex.
JTCVS open
|January 9, 2025
概括
在接受大动脉手术的患者中使用大麻与中风和呼吸系统问题的风险更高有关. 虽然整体死亡率相似,但大麻使用者面临的紧急程序和并发症更多.
科学领域:
- 心血管外科心血管外科
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 大麻使用很普遍,但它对手术结果的影响,特别是在复杂的心血管手术中,如大动脉动脉瘤或剖析修复,仍未得到充分研究.
- 了解这些风险对于患者分层和术后管理至关重要.
研究的目的:
- 评估在接受大动脉动脉瘤或剖析修复的患者中术前大麻消费与中长期手术结果之间的关联.
- 在这个患者群体中确定与大麻使用相关的特定并发症和风险因素.
主要方法:
- 对134名大麻使用者和非使用者进行了回顾性分析,这些人于2007年至2023年间接受了大动脉手术.
- 患者根据手术前的大麻使用史进行了分层.
- 结果包括30天的并发症,死亡率,晚期并发症和重新干预.
主要成果:
- 大麻使用者比较年轻,患马芬综合征的频率更高,并报告了更多的娱乐性药物使用率 (可卡因,安非他命,阿片类药物) 和紧急手术.
- 手术死亡率在两组之间是可比的 (9.7%对比8.6%).
- 大麻使用者经历的术后中风 (14.9%与8.2%) 和呼吸道并发症 (32.1%与19.0%) 的比率显著更高.
结论:
- 大麻使用与大动脉手术后脑血管事故和呼吸道并发症的风险增加有关.
- 长期使用大麻可能表明风险较高,因此在年轻患者中需要更多的紧急干预.
- 大麻的消费被认为是大动脉手术结果的重要风险因素.
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