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Updated: Jun 3, 2025

A Workflow for Lipid Nanoparticle LNP Formulation Optimization using Designed Mixture-Process Experiments and Self-Validated Ensemble Models SVEM
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A Workflow for Lipid Nanoparticle LNP Formulation Optimization using Designed Mixture-Process Experiments and Self-Validated Ensemble Models SVEM

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固体脂质纳米颗粒的配方设计,优化和评估,载有抗病毒药物诺福维尔,使用盒式设计来提高口服生物可用性

Sri Rekha M1, Sangeetha S1

  • 1Department of Pharmaceutics, SRM College of Pharmacy, SRMIST, Kattankulathur, Chennai, Tamil Nadu, India.

Advances in pharmacological and pharmaceutical sciences
|January 9, 2025
PubMed
概括

这项研究开发了固体脂质纳米颗粒 (SLN),以提高艾滋病毒药物诺福维尔 (TNF) 的口服生物可用性. 优化的SLN显著改善了药物输送,为生物可用性挑战提供了一个有希望的解决方案.

关键词:
康普里托尔 888 ATO 公司纳米载体的纳米载体风险评估 风险评估 风险评估固体脂质纳米粒子 固体脂质纳米粒子这种药物是tenofovir.

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