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Updated: Jun 3, 2025

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USP25稳定STAT6,促进IL-4诱导的巨细胞M2极化和纤维化

Yahan Xu1, Jing Liu2, Jingzeng Wang2

  • 1Department of Respiratory and Critical Care Medicine, National Clinical Research Center of Respiratory Disease, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

International journal of biological sciences
|January 9, 2025
PubMed
概括

乌比基特异性化酶25 (USP25) 缺乏通过减少M2巨分化来保护器官纤维化. USP25抑制STAT6/PPAR-γ信号提供了纤维性疾病的潜在治疗标.

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