基于天然凝的药物输送系统:全球情景,当前发展和未来的前景
Momin Firdose Abdul Shukur1, Shivani Makhijani2, Rahul Ingle2
1Department of Pharmaceutics, Y. B. Chavan College of Pharmacy, Aurangabad, India.
Current drug delivery
|January 9, 2025
概括
水凝是先进的生物材料,拥有日益增长的全球市场,提供可控的药物输送和多样化的应用. 它们的独特特性提高了治疗效果,尽管制造成本仍然是一个挑战.
科学领域:
- 生物材料科学 生物材料科学
- 聚合物化学 聚合物化学
- 制药科学 制药科学
背景情况:
- 水凝是水友性聚合物的3D网络,在生物材料科学中取得了重大进展.
- 全球基于水凝的药物输送系统市场正在迅速扩大,预计到2030年将达到12.357亿美元.
- 水凝具有生物相容性,生物降解性和高药物载荷能力,使其非常适合各种应用.
研究的目的:
- 审查水凝的基本方面,包括其分类和全球市场趋势.
- 突出基于水凝的药物输送系统 (DDS) 的当前发展和潜在应用.
- 讨论水凝在治疗应用中的优缺点.
主要方法:
- 对水凝特性,应用和市场趋势的文献综述.
- 分析基于水凝的DDS当前的研发情况.
- 讨论水凝的优点,如受控释放和生物相容性,以及成本等限制.
主要成果:
- 水凝通过触发响应释放 (pH,温度,酶) 促进向药物递送.
- 它们保护不稳定的药物,使多种药物封装成为可能,并提高生物可用性和患者遵守性.
- 应用范围包括药物输送,组织工程,伤口愈合,化品和医疗器械.
结论:
- 水凝是多功能生物材料,具有改善治疗药物输送结果的巨大潜力.
- 持续的进步有望实现更高效和有效的基于水凝的DDS.
- 尽管存在诸如制造成本等挑战,但水凝是许多生物医学应用中首选的选择.
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