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相关概念视频

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

346
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
346
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

2.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.6K
Asthma-I: Introduction01:29

Asthma-I: Introduction

2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

230
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by...
230

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相关实验视频

Updated: Jun 3, 2025

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
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A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

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孕产妇高脂肪饮食计划后代的呼吸道过敏和过敏反应.

Kayla R Williams, Hoyt Atk Bright, Allison D Fryer

    JCI insight
    |January 9, 2025
    PubMed
    概括

    由于高脂肪饮食导致的孕产妇肥胖会导致代谢功能障碍和后代的呼吸道过敏反应. 这项研究强调了母亲的饮食如何影响后代喘风险.

    科学领域:

    • 免疫学 免疫学 免疫学
    • 发展生物学 发展生物学
    • 呼吸系统医学 呼吸系统医学

    背景情况:

    • 孕产妇肥胖是一个日益严重的全球健康问题.
    • 母亲饮食对后代呼吸系统健康,特别是喘的影响尚未完全理解.
    • 后代的遗传多样性可能会影响对饮食诱导影响的易感性.

    研究的目的:

    • 为了研究由饮食引起的孕产妇肥胖对后代呼吸道过敏反应的影响.
    • 探索将母亲饮食与后代呼吸功能障碍联系在一起的潜在机制.
    • 利用反映人类遗传多样性的小鼠模型.

    主要方法:

    • 在怀孕和哺乳期间和之前,雌性小鼠被食高脂肪或定期饮食.
    • 后代在断奶后得到正常的饮食.
    • 气道过敏反应,体重,脂肪量,代谢参数和气道内置在不同的时间点被评估.

    主要成果:

    • 被养高脂肪饮食的母婴的后代表现出体重增加,脂肪量增加,代谢功能障碍和高胰岛素血症.
    • 这些后代的呼吸道上皮质感官内置和支气管收缩增加.
    • 支气管收缩是由神经介导的,可以通过阴道切除或缩来阻止,这表明反射介导的反应.
    关键词:
    喘 喘 是一种脑内神经转化 (英语:innervation,英语:innervation) 是一种神经转化.胰岛素是一种胰岛素.代谢过程中的代谢.肺部病理学 肺部病理学

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    Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
    07:13

    Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C

    Published on: March 25, 2016

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    相关实验视频

    Last Updated: Jun 3, 2025

    A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
    08:50

    A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

    Published on: June 24, 2020

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    Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
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    Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
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    结论:

    • 饮食引起的孕产妇肥胖,特别是在怀孕前,显著影响后代的呼吸道生理学.
    • 孕产妇的代谢功能障碍和高胰岛素血症有助于后代的超内内和呼吸道过敏反应.
    • 这些发现提供了关于喘遗传和母亲环境在遗传多样性人口中的作用的见解.