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在皮埃尔·罗宾序列的管理中,下干扰骨质生成与气管切除术:系统性审查和元分析

Indri Lakhsmi Putri^1,2, Kusuma Islami², Imaniar Fitri Aisyah³

¹Department of Plastic Reconstructive and Aesthetic Surgery, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

|January 9, 2025

概括

在皮埃尔·罗宾序列 (PRS) 患者的严重气道阻塞管理方面,部分心骨质生成 (MDO) 优于气管切除术. MDO改善了呼吸道结果,减少了输送管的需求,并降低了成本,使其成为首选的治疗方法.

科学领域:

面外科手术面外科手术
儿科气道管理儿童气道管理
手术创新在外科创新.

背景情况:

严重的呼吸道阻塞是皮埃尔·罗宾序列 (PRS) 患者的关键挑战.
目前的管理策略包括气管切除术和下分心骨质生成 (MDO).
这些干预措施在PRS中的比较有效性数据有限.

研究的目的:

系统地比较MDO与气管切除术在治疗PRS患者严重气道阻塞方面的疗效.
评估MDO和气管切除术之间的气道管理,养结果和医疗保健成本的差异.

主要方法:

一个系统的审查和元分析,遵循PRISMA指南.
在主要数据库 (PubMed,Scopus,Web of Science等) 进行全面的文献搜索. 在2024年5月之前.
使用纽卡斯尔-太华尺度对所包含研究的质量评估.

主要成果:

与气管切开术相比,MDO,特别是MDO-first方法,显示出明显更好的气道结果.
MDO显著降低了胃口管 (G-管) 放置的要求.
MDO与医院费用大幅降低有关,尽管住院时间没有显著差异.

结论:

在皮埃尔·罗宾序列 (PRS) 患者中,部分心骨质生成 (MDO) 为严重的呼吸道阻塞提供了优越的治疗选择.
在气道管理方面,MDO提供了优势,减少了对料管的需求,并大大节省了成本.
建议在同质综合征组内进行进一步的大规模研究,以证实这些发现.

关键词:

皮埃尔·罗宾的序列气道阻塞气道阻塞气道阻塞下分心骨质生成骨质生成医疗保健. 医疗保健. 在医疗保健.气管修复术 (tracheostomy) 是一种呼吸道修复术.

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