上肢运动能力和肌肉氧化在患有初级动力失速症的患者中
Şeyma Mutlu1, Meral Boşnak Güçlü2, Tuğba Şişmanlar Eyüboğlu3
1Department of Physical Therapy and Rehabilitation, Faculty of Health Sciences, Başkent University, Ankara, Turkey.
Pediatric pulmonology
|January 9, 2025
概括
患有原发性纤维动力障碍 (PCD) 的儿童显示肺功能减弱和上肢肌肉强度下降. 然而,他们的上肢运动能力被保留,尽管静止肌肉的氧和度较低.
科学领域:
- 儿科肺病学 儿科肺病学
- 运动生理学 运动生理学
- 罕见疾病 罕见疾病
背景情况:
- 原发性纤维动力障碍 (PCD) 是一种影响粘膜纤维清除的遗传性疾病.
- 减少运动能力是PCD患者已知的并发症.
- 关于儿科PCD上肢功能能力的研究有限.
研究的目的:
- 为了比较PCD儿童的肺功能与对照.
- 评估上肢的功能性运动能力,肌肉氧化和力量.
- 评估PCD儿童的体力活动水平.
主要方法:
- 27名患有PCD的儿童和26名对照参与了这项研究.
- 通过螺旋测量评估肺功能.
- 使用6分钟板和环测试 (6PBRT) 评估上肢功能,肌肉氧化 (Moxy),骨强度 (动力计) 和体力活动 (代谢性holter).
主要成果:
- 与对照人群相比,PCD患者的FVC%,FEV1%,FEV1/FVC,PEF%,FEF25%-75%,以及骨髓肌肉强度显著降低 (p <0.05).
- 在6PBRT环数或deltoid肌肉氧和和组之间的血红蛋白水平之间没有发现显著差异 (p > 0.05).
结论:
- 患有PCD的儿童经历了肺功能减弱和上肢肌肉强度的下降.
- 在儿科PCD中,上肢运动能力保持不变,但静止肌肉的氧和度降低.
- 对PCD的肺部康复计划应包括运动训练和体育活动咨询.
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