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通过EZH2调节miR-155-5p的下调,通过SMAD2和TAB2促进前列腺癌细胞恶性瘤

Zhi-Jie Bai1, Jia-Yi Liu1, Wen-Zhou Xing1

  • 1Department of Urology, Tianjin First Central Hospital, Tianjin, China.

The Kaohsiung journal of medical sciences
|January 9, 2025
PubMed
概括

前列腺癌 (PCa) 涉及减少miR-155-5p表达由于增强剂的zeste 2 (EZH2) 介导的促进物甲基化. 这种表观遗传调节通过上调SMAD2和TAB2.2,促进PCa细胞的增殖和入侵.

关键词:
在 EZH2 中使用.这就是SMAD2的原因.TAB2 TAB2 的时间表.在 miR-155-5p 中, miR为155-5p.前列腺癌是前列腺癌.

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