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Updated: Jun 3, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

Published on: October 6, 2014

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乳腺癌易感性 基因序列变异和逆侧乳腺癌的发展

Anne S Reiner1, Gordon P Watt1, Kathleen E Malone2

  • 1Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.

JAMA network open
|January 9, 2025
PubMed
概括

乳腺癌基因中的有害生殖系变异与特定的雌激素受体 (ER) - 阳性和ER - 阴性逆侧乳腺癌 (CBC) 的发展有关. 第一次原发性乳腺癌的ER状态并没有改变这些关联.

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Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
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