住院的上肢动脉疾病患者:治疗和长期结果
Lena Makowski1, Christiane Engelbertz1, Jeanette Köppe2
1Department of Cardiology I-Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Muenster, Cardiol, Albert-Schweitzer-Campus 1, Muenster D-48149, Germany.
European heart journal
|January 9, 2025
概括
患上肢动脉疾病 (UEAD) 的患者预后不佳,截肢和死亡率高. 男人面临更大的心血管和肢体事件的风险,包括死亡,突出了UEAD结果中与性别相关的差异.
科学领域:
- 血管医学 血管医学
- 流行病学 流行病学
- 基于性别的健康差异
背景情况:
- 关于上肢动脉疾病 (UEAD) 的知识有限.
- 这项研究调查了UEAD患者的患病率,治疗和结果.
研究的目的:
- 评估UEAD的流行率和治疗模式.
- 评估UEAD患者的短期和长期结果.
- 在UEAD中发现与性别相关的差异.
主要方法:
- 对2010-2017年健康声明数据的回顾性分析.
- 包括2437名住院治疗UEAD的患者.
- 评估风险因素,并发症,药物治疗,再血管化和结果,重点关注性别差异.
主要成果:
- 80%的UEAD病例是动脉样硬化 (UEADa),20%是炎症/连接组织疾病 (UEADc/i).
- 与女性相比,男性患心血管疾病,器官衰竭和肢体截肢的比例更高.
- 五年死亡率总体接近50%,男性更高;女性的再血管化率更高.
结论:
- UEAD患者面临的预后不佳,截肢和死亡率高.
- 男人与心血管事件,肢体事件和死亡风险增加有关.
- 需要进一步的研究来理解和解决UEAD治疗和结果的基于性别的差异.
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