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Updated: Jun 3, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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阐明向ATP结合盒子子子家族G成员2 (ABCG2) 的相互作用化合物的结合特异性

Pawan Kumar1, Indu Kumari2,3, Rajendra Prasad2

  • 1School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India.

Molecular diversity
|January 9, 2025
PubMed
概括

分子对接和模拟揭示了基板和抑制剂如何与ABCG2 (乳腺癌抵抗蛋白) 结合. 多塞塔克塞尔,塔里基达尔和特扎卡夫托尔表现出高的结合亲缘关系,有助于理解耐药性.

关键词:
在ABC运输器上,运输器是ABC.这是ABCG2/BCRP.抑制剂的抑制剂模拟MDMD的模拟分子对接是分子对接.多种药物耐药性多种药物耐药性这是POPC的POPC.基板 基板是一种基板.塔里奎达尔 (塔里奎达尔) 是一个历史人物.

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