植物性饮食对类风湿关节炎的影响:系统性审查
Zekiye Zeynep Bostan1, Melike Şare Bulut2, Buket Özen Ünaldı3
1Department of Nutrition and Dietetics, İstanbul Gedik University, 34906 İstanbul, Türkiye.
Nutrition reviews
|January 9, 2025
概括
植物性饮食,包括地中海饮食,在减少类风湿性关节炎 (RA) 严重程度和改善患者标志物方面表现有前途. 需要进一步的研究来证实这些益处,并指导RA管理的饮食策略.
科学领域:
- 类风湿病学 类风湿病学
- 营养科学 营养科学
- 系统审查是系统的审查.
背景情况:
- 类风湿性关节炎 (RA) 是一种慢性自身免疫性疾病,导致关节炎症和损伤.
- 饮食干预措施,特别是植物性饮食,正在研究它们对RA症状和疾病活动的潜在影响.
研究的目的:
- 系统地审查有关各种植物性饮食对类风湿性关节炎 (RA) 影响的现有文献.
- 综合有关地中海,低脂肪,高碳水化合物,抗炎和素食饮食对RA疾病活动和临床标志物的影响的研究结果.
主要方法:
- 在主要数据库 (Web of Science,PubMed,Scopus,Cochrane) 进行了系统的文献搜索.
- 包括的研究是观察性或干预性,专注于成年人,以英语出版 (2013年2月至2023年4月),并使用Joanna Briggs Institute检查清单评估偏见风险.
- 分析了15项研究 (4项截面研究,2项队列研究,9项RCT).
主要成果:
- 坚持植物性饮食通常与减少RA疾病严重程度相关.
- 在饮食摄入量,体力活动,体重和临床标志物 (DAS-28,VAS,HAQ-DI,ESR,CRP) 中观察到改善.
- 地中海饮食经常与RA严重程度的积极影响有关.
结论:
- 植物性饮食,特别是地中海饮食,可能会积极影响类风湿性关节炎 (RA) 的严重程度.
- 研究之间的异质性需要进一步进行高质量的随机对照试验.
- 更多的研究对于了解饮食在RA中的作用和告知预防策略至关重要.
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