通过抑制JAK2/STAT3通路,SLC27A3下调恢复了Th17/Treg平衡,并通过抑制JAK2/STAT3通路缓解了COPD

Xiaoping Li1, Ji Liu2, Zehui Jing1

  • 1Department of Geriatric Medicine, Qinghai University Affiliated Hospital, Xining, Qinghai, China.

PubMed
概括

在慢性阻塞性肺病 (COPD) 的小鼠中降低调节溶解物载体家族27成员3 (SLC27A3) 改善肺功能并减少炎症. 这通过抑制JAK2 / STAT3途径,重新平衡Th17 / Treg细胞并减轻COPD进展而发生.

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