中度至强度的体力活动不会改善2型糖尿病患者的死亡率,这些患者有严重的腹腔大动脉化
Chang Sheng1, Yacheng Xiong1, Pu Yang1,2,3
1Department of Vascular Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
PloS one
|January 9, 2025
概括
严重的腹腔大动脉化 (SAAC) 强烈预测2型糖尿病 (T2D) 患者的死亡率. 中度至强度的体力活动 (MVPA) 似乎没有改善这种高风险人群的生存率.
科学领域:
- 心血管健康 心血管健康
- 糖尿病管理 糖尿病管理
- 公共卫生 公共卫生
背景情况:
- 在2型糖尿病 (T2D) 患者中,身体活动和死亡率与严重腹腔大动脉化 (SAAC) 的相关性尚不清楚.
- 腹腔大动脉化 (AAC) 是血管疾病的标志物,SAAC表明一种严重的形式.
- 了解体育活动在这个特定子组中的作用对于风险分层和风险管理至关重要.
研究的目的:
- 调查中度至强度体力活动 (MVPA) 对2型糖尿病 (T2D) 严重腹腔大动脉化 (SAAC) 患者全因死亡率的影响.
主要方法:
- 分析了2013-2014年国家健康和营养检查调查 (NHANES) 的数据.
- 包括40岁及以上的T2D患者,SAAC定义为Kauppila分数>6.6,包括40岁及以上的T2D患者.
- 使用加权考克斯回归来评估SAAC,MVPA和全因死亡率之间的关联.
主要成果:
- 严重的腹腔大动脉化 (SAAC) 在权重样本的16.39% (20,328,606名T2D参与者) 中存在.
- 在调整了混杂因素后,SAAC与所有原因死亡风险增加2.57倍 (95% CI 1.52-4.35) 有显著关联.
- 中度至强度的体力活动 (MVPA) 在SAAC的T2D患者中没有显著降低死亡风险 (HR 1.00,95% CI 0.40-2.49).
结论:
- 严重的腹腔大动脉化 (SAAC) 是2型糖尿病 (T2D) 患者死亡率的重要预测因素.
- 中度至强度的体力活动 (MVPA) 似乎没有减轻SAAC.T2D患者的死亡风险.
- 需要进一步的研究,以探索在这个高风险人群中对MVPA指示的特定子组分析.
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