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在神经神经调节后手术部位感染:术后抗生素的影响

Luke J King¹, Sarah L Ashmore², Hannah L Chapman³

¹From the Division of Urogynecology and Reconstructive Pelvic Surgery at the Women and Infants Hospital, Providence, RI.

Urogynecology (Philadelphia, Pa.)

|January 9, 2025

概括

预防性术后抗生素在移植神经调节装置后对减少手术部位感染的效果很小. 感染率仍然很低,这表明目前的做法可能不会显著影响结果.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
传染性疾病传染性疾病
手术创新在外科创新.

背景情况:

手术部位感染 (SSIs) 是神经神经调节 (SNM) 装置植入后的一个担忧.
仅有有限的数据可指导预防性抗生素在SNM程序中预防SSI的使用.

研究的目的:

为了比较在接受预防性术后抗生素的患者和在SNM设备植入后没有接受抗生素的患者中SSI的发病率.
评估预防性抗生素在SNM程序中对SSI的影响.

主要方法:

一项多中心回顾性队列研究包括1798名从2014年到2023年接受SNM设备植入的患者.
在接受预防性术后抗生素和未接受抗生素的患者之间比较了结局.
90天内手术部位感染是主要结局,进行回归分析以确定相关变量.

主要成果:

在1798名患者中,共发现67例SSI (3.7%).
在SSI率 (3.6%对3.9%,P=0.8) 或设备探索 (2.0%对2.8%,P=0.2) 中没有观察到群体之间的显著差异.
根据年龄调整的多变量分析显示,预防性抗生素使用与减少的SSI无关 (OR 0.98,95% CI:0.61-1.61,P = 0.94).

结论:

在神经神经调节装置植入后,手术部位感染率很低.
预防性术后抗生素的使用似乎对减少这一患者群体的SSI的影响很小.
需要进一步的研究,以了解在SNM程序中影响SSI的因素.

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