深度大脑刺激 - - 精神病学家的入门教程
Lavanya P Sharma1, Uma Maheswari Ganesh2, Shyam Sundar Arumugham1
1OCD Clinic, Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), India.
Asian journal of psychiatry
|January 9, 2025
概括
深度大脑刺激 (DBS) 为严重精神疾病提供了手术的替代方案. 本综述涵盖了DBS的征兆,证据,机制以及对抗治疗性疾病的未来研究.
科学领域:
- 神经科学是一个神经科学.
- 神经外科 神经外科
- 精神病学是一个精神病学.
背景情况:
- 深度大脑刺激 (DBS) 涉及通过植入的电极对脑目标进行电刺激.
- 它正在成为精神病患者的消退性手术的替代品.
- 对于患有对常规疗法耐药性疾病的患者,可以考虑使用DBS.
研究的目的:
- 审查DBS的精神病学适应症.
- 总结目前支持精神病学DBS的证据.
- 探索精神疾病的DBS的假定机制和未来方向.
主要方法:
- 关于精神疾病的深度大脑刺激研究的文献综述.
- 对临床证据,机械学假设和未来研究趋势的分析.
主要成果:
- DBS越来越多地适用于对标准治疗耐药的特定精神疾病.
- 在精神疾病中DBS疗效的证据基础正在增长.
- 讨论了假定机制和未来的研究途径.
结论:
- 深度大脑刺激是一种可行的治疗选择,用于选择精神疾病.
- 需要进一步的研究来优化DBS目标,参数和患者选择.
- 对于推进耐治疗精神病治疗,DBS是有前途的.
相关概念视频
The Scientific Method
57.2K
Research is what makes the difference between facts and opinions. Facts are observable realities, and opinions are personal judgments, conclusions, or attitudes that may or may not be accurate. In the scientific community, facts can be established only using evidence collected through empirical research.
57.2K
Long-term Depression
2.6K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
Calcium Ion Concentration Mechanism
If over...
2.6K
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
2.5K
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
2.5K
Introduction to Biological Bases of Psychology
5.8K
Biopsychology serves as a vital bridge connecting the intricate domains of biology and psychology, shedding light on how biological systems influence psychological phenomena. This field scrutinizes the biological substrates of behavior and mental processes, emphasizing the nervous system along with the roles of neurotransmitters, hormones, and genetics. It also incorporates evolutionary perspectives to explain the adaptive nature of mental functions.
The nervous system, the cornerstone of...
The nervous system, the cornerstone of...
5.8K
Introduction to Cognitive Psychology
2.7K
Cognitive psychology is the field of psychology dedicated to examining how people think. It attempts to explain how and why we think the way we do by studying the interactions among human thinking, emotion, creativity, language, and problem-solving, as well as other cognitive processes. Cognitive psychology studies how information is processed and manipulated in remembering, thinking, and knowing.
This field emerged in the mid-20th century, following a period dominated by behaviorism, which...
This field emerged in the mid-20th century, following a period dominated by behaviorism, which...
2.7K
Dementia l: Introduction
35
Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
35


