Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

35
Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
35
Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

36
Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
 Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle...
36
Horney's Sociocultural Approach01:27

Horney's Sociocultural Approach

441
Karen Horney's psychoanalytic theories emphasize the potential for self-realization and the importance of addressing social and cultural, rather than biological, factors in personality development. She challenged traditional Freudian views, particularly Freud's concept of "penis envy," which she argued stemmed from cultural influences rather than inherent biological differences. Horney believed that any sense of inferiority in women was a result of societal conditioning, such as...
441
Personality Disorders: Schizotypal and Histrionic01:20

Personality Disorders: Schizotypal and Histrionic

52
Schizotypal personality disorder and histrionic personality disorder are two distinct psychological conditions classified under personality disorders, each characterized by unique behavioral patterns and social difficulties. Both disorders significantly affect interpersonal relationships and emotional well-being, leading to social isolation and frustration.
Schizotypal Personality Disorder: Eccentric Behavior and Social Withdrawal
Schizotypal personality disorder is marked by odd or eccentric...
52
Personality Disorders: Paranoid and Schizoid01:22

Personality Disorders: Paranoid and Schizoid

29
Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...
29
Self-Discrepancy Theory02:45

Self-Discrepancy Theory

18.3K
One influential perspective on what motivates people's behavior is detailed in Tory Higgin's self-discrepancy theory (Higgins, 1987). He proposed that people hold disagreeing internal representations of themselves that lead to different emotional states.  
18.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Regional, functional and transcriptomic decoding of multidimensional brain structure alterations in obsessive-compulsive disorder.

Nature communications·2026
Same author

Neural correlates of mental illness related stigma: a systematic review of neuroimaging evidence.

Journal of psychiatric research·2026
Same author

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Encephalitis With Cerebrospinal Fluid Polymerase Chain Reaction (PCR) Positivity and Normal Neuroimaging: A Case Report.

Cureus·2026
Same author

Causal interhemispheric neuromodulation sharpens synaptic and neurobehavioral inhibition in stroke.

Brain communications·2026
Same author

Disseminated Intravascular Coagulation With a Predominant Thrombotic Phenotype in Severe Plasmodium falciparum Malaria: A Case Report.

Cureus·2026
Same author

Prognostic Impact of Cumulative Fluid Balance in Critically Ill Patients: A Retrospective Cohort Study.

Cureus·2026

相关实验视频

Updated: Jun 3, 2025

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

15.4K

在强迫症障碍中的"演员-关键"二分类过度激活和低连接性.

Ana Araújo1, Isabel C Duarte2, Teresa Sousa3

  • 1Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, 3000-548 Coimbra, Portugal; Institute for Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, 3000-548 Coimbra, Portugal; Institute of Psychological Medicine, Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal; Faculty of Medicine, Institute of Physiology, University of Coimbra, 3004-531 Coimbra, Portugal; Department of Psychiatry, Local Health Unit of Coimbra, 3004-561 Coimbra, Portugal.

NeuroImage. Clinical
|January 9, 2025
PubMed
概括

强迫症 (OCD) 涉及受损的反应抑制,在"演员"和"关键"区域具有独特的大脑活动模式. 这些神经差异与症状严重程度相关,并可能为新疗法提供信息.

关键词:
演员-评论家 演员-评论家尾巴状的 尾巴状的 尾巴状的错误监控 错误监控 错误监控 错误监控 错误监控 错误监控抑制抑制的抑制作用强迫症是一种强迫性障碍.普塔曼 (Putamen) 是一个名为普塔曼 (Putamen) 的男子.腹部顶部区域的区域.

更多相关视频

Real-time fMRI Biofeedback Targeting the Orbitofrontal Cortex for Contamination Anxiety
10:51

Real-time fMRI Biofeedback Targeting the Orbitofrontal Cortex for Contamination Anxiety

Published on: January 20, 2012

21.3K
Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
06:50

Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice

Published on: December 24, 2013

28.3K

相关实验视频

Last Updated: Jun 3, 2025

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

15.4K
Real-time fMRI Biofeedback Targeting the Orbitofrontal Cortex for Contamination Anxiety
10:51

Real-time fMRI Biofeedback Targeting the Orbitofrontal Cortex for Contamination Anxiety

Published on: January 20, 2012

21.3K
Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice
06:50

Marble Burying and Nestlet Shredding as Tests of Repetitive, Compulsive-like Behaviors in Mice

Published on: December 24, 2013

28.3K

科学领域:

  • 神经科学是一个神经科学.
  • 认知心理学 认知心理学
  • 精神病学是一个精神病学.

背景情况:

  • 响应抑制功能障碍与强迫症 (OCD) 有关,但神经机制尚不清楚.
  • 现有的模型无法完全整合强迫症的抑制,错误处理和行为相关性.

研究的目的:

  • 通过使用演员-关键框架,研究强迫症中反应抑制和错误处理的神经机制.
  • 为了将大脑活动和连接性与强迫症患者的行为测量和症状严重程度相关联.

主要方法:

  • 功能性磁共振成像 (fMRI) 在停止信号任务期间在19名强迫症成年人和21名健康对照中进行.
  • 分析演员 (条形体) 和批评者 (中脑) 区域的大脑激活和功能连接.
  • 神经测量与行为表现 (缓慢) 和强迫症症状严重程度的相关性.

主要成果:

  • 强迫症患者在应对准备过程中,关键区域和前置控制区域之间的连接性降低.
  • 在强迫症中观察到与任务相关的中脑过度激活和错误处理期间的条纹性过度激活,这与行为缓慢有关.
  • 腹部 tegmental 区域 (演员) 和尾部 (关键) 活动之间的对立关系影响了强迫症症状的严重程度.

结论:

  • 强迫症中独特的演员关键神经特征是"避免伤害"反应抑制的基础,并影响症状严重程度.
  • 低连接性和过度激活模式表明强迫症中的神经适应机制.
  • 这些发现为强迫症治疗的神经生物学知情治疗策略提供了潜力.