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由N-甘化修饰驱动的结构动力学减弱了d-lactonohydrolase的基质抑制

Ruobin Sun1, Qipeng Yan2, Wenhao Deng3

  • 1School of Biotechnology and Key Laboratory of Industrial Biotechnology of Education, School of Biotechnology, Jiangnan University, Wuxi 214122 China.

Bioorganic chemistry
|January 9, 2025
PubMed
概括

在真核宿主中,d-lactonohydrolase (d-Lac) 的糖化减少了高度的酶基质抑制,通过调节活性位点循环的灵活性. 这提高了工业应用的生物催化效率.

关键词:
符合性的动态学.葡萄糖基酶化是什么? 葡萄糖基酶化的方法马尔科夫状态模型的模型.分子动力学分子动力学蛋白质组学是指蛋白质组学.基质抑制 基质抑制d-Lactonohydrolase 的使用情况

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