右心房功能对三回患者的预后和功能的影响
Elvin Tafciu1, Matteo Pilan1, Bianca Rocca1
1Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy.
The American journal of cardiology
|January 9, 2025
概括
在三回 (TR) 患者中,右心房应力 (RAS) 降低预测死亡率和功能恶化. 测量RAS为TR患者提供了有价值的预后信息.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 腎臟醫學 腎臟醫學
背景情况:
- 三回 (TR) 影响生存,右心房 (RA) 尺寸和功能可能发挥关键作用.
- 使用菌株 (RA菌株[RAS]) 评估RA功能可能为TR提供预后见解.
- 末端器官拥堵,特别是功能,是TR管理中的一个关键问题.
研究的目的:
- 评估RA功能,特别是RAS对TR患者患者患者结果和末端器官拥堵的影响.
- 确定RAS是否是死亡率,心力衰竭住院和功能恶化 (WRF) 的独立预测因素.
- 评估RAS在已确定的临床和心声学参数上的增量预测值.
主要方法:
- 一项前性研究,涉及134名患有TR任何级别或病因的患者,接受完整的心声和功能评估.
- 随访时间中位数为23.5个月,以评估主要终点 (死亡率和右侧心力衰竭住院治疗) 和二次终点 (WRF).
- 使用多变量回归分析来确定结果的独立预测因素,并根据相关的共变量进行调整.
主要成果:
- 患有RAS≤18%的患者的无事件存活率显著降低 (日志数等级p <0.001).
- RAS ≤18%和肺动脉静脉压升高 (PASP) 是主要终点和WRF的独立预测因素.
- RAS ≤18%为WRF提供了超越PASP和其他心声回声测量的增量预测能力.
结论:
- 右心房应变 (RAS) 是三回 (TR) 患者死亡率和住院病例的独立预测因素.
- 通过RAS测量的减少的RA功能,独立预测TR患者的功能恶化 (WRF).
- RAS测量提供了有价值的预后信息,并增强TR患者的风险分层,特别是在功能方面.
更多相关视频
08:10Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
1.6K
10:39Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
Published on: August 30, 2024
547
相关概念视频
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
381
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
381
Heart Failure Drugs: Diuretics
338
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
338
Factors Affecting Renal Clearance: Renal Impairment
53
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
53
