在定期的囊性纤维化治疗中长期采用家庭螺旋计:回顾性多中心观察性研究
Pia Bertram1, Martinus C Oppelaar1, Michiel Age Bannier2
1Department of Pediatric Pulmonology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
Journal of medical Internet research
|January 9, 2025
概括
在囊性纤维化 (CF) 患者的长期家庭螺旋计使用率很低,超过一半的患者在一年内停止使用. 然而,随着肺部症状恶化,使用量增加,这表明在症状监测中发挥了作用.
科学领域:
- 肺部医学 肺部医学
- 医疗技术 医疗技术 医学技术
- 数字健康数字健康
背景情况:
- 家庭螺旋仪在囊性纤维化 (CF) 护理中用于早期检测恶化.
- 对于CF患者来说,长期坚持家庭螺旋计仍然是一个挑战.
研究的目的:
- 调查家庭螺旋计在常规囊性纤维化治疗中的长期采用和一致性.
- 了解随着时间的推移影响家庭螺旋计使用模式的因素.
主要方法:
- 从5个荷兰中心的604名CF患者的家庭螺旋计使用数据的回顾性分析 (2020年4月至2022年12月).
- 生存分析评估了使用的一致性;t测试评估了症状影响;ANOVA检查了Elexacaftor/Tezacaftor/Ivacaftor治疗的影响.
- 使用了与家用螺旋计集成的远程监控平台.
主要成果:
- 开始后家庭螺旋计使用者的快速下降;54.2%在一年内停止使用.
- 只有11.1%的用户进行了超过20次测量;随着时间的推移,一致的使用量显著下降.
- 使用频率随着肺部症状的增加而增加,但在新的CFTR调节器疗法下显示出最初的增加,然后下降.
结论:
- 在CF患者中,一致的长期家庭螺旋计吸收率很低.
- 使用强度与症状变化相关,表明可能需要监测.
- 结构化的远程护理策略和个性化的目标设定对于改善家庭螺旋计的坚持和效用至关重要.
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