用混合闭环系统对1型糖尿病青少年三种不同运动类型的葡萄糖和额外信号进行比较
Rowen Seckold1,2,3,4, Carmel E Smart1,2,3,4, David N O'Neal5,6
1Department of Paediatric Diabetes and Endocrinology, John Hunter Children's Hospital, New Lambton Heights, New South Wales, Australia.
Diabetes technology & therapeutics
|January 9, 2025
概括
在患有1型糖尿病 (T1D) 的青少年中使用混合闭环胰岛素可以在运动期间保持良好的血糖控制. 在运动后调整暂时的葡萄糖目标,可能进一步降低低血糖的风险.
科学领域:
- 内分泌学 在内分泌学.
- 儿科 儿科 儿科
- 运动医学 运动医学
背景情况:
- 患有1型糖尿病 (T1D) 的青少年在体育活动期间面临管理血糖的挑战.
- 混合闭环 (HCL) 胰岛素系统提供先进的血糖控制,但需要对炼进行优化.
研究的目的:
- 用HCL系统比较T1D青少年中中等强度运动 (MIE),高强度间歇运动 (HIE) 和抵抗运动 (RE) 的血糖结果和生理反应.
- 为了评估运动前和运动期间设置的临时葡萄糖目标的有效性.
主要方法:
- 28名患有T1D的青少年使用HCL参加了40分钟的MIE,HIE和RE会议.
- 在运动前2小时和运动期间实施了8.3mmol/L的临时葡萄糖目标.
- 持续的葡萄糖监测,心率,乳酸盐,和对调节激素被测量了运动开始后280分钟.
主要成果:
- 高强度间歇运动 (HIE) 和抵抗运动 (RE) 与中等强度运动 (MIE) 相比,在范围内的时间 (TIR) 更长.
- 低血糖症发生在很大一部分参与者身上,主要发生在运动后的饭后.
- 在HIE和RE期间,与MIE相比,观察到乳酸,生长激素,上腺素和心率的升高.
结论:
- 具有预设的临时葡萄糖目标的HCL系统,在患有T1D的青少年中,在各种运动类型中促进了出色的血糖控制.
- 运动后对暂时的葡萄糖目标进行调整可能是必要的,以减轻低血糖风险.
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