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Updated: Jun 3, 2025

Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
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接近红外的基RNA用于体内成像和传感

Zhenyin Chen1,2,3, Wei Chen4,5, Cun Xu6,7

  • 1Interdisciplinary Science Center, State Key Laboratory of Integrated Management of Pest Insects and Rodents,Institute of Zoology, Chinese Academy of Sciences, 100101, Beijing, China.

Nature communications
|January 9, 2025
PubMed
概括

研究人员开发了一种新的近红外 (NIR) 光RNA标签,使用一种名为Squash的化RNA和一种光 DFQL-1T. 这一进步使得活细胞和动物中的RNA可视化和传感能够用于体内成像应用.

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相关概念视频

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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