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Updated: Jun 3, 2025

A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates
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菌体卫星P4的Psu蛋白通过强制超寡合化抑制转录终结因子 ρ

Daniela Gjorgjevikj1,2, Naveen Kumar3, Bing Wang4

  • 1Laboratory of Structural Biochemistry, Institute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.

Nature communications
|January 9, 2025
PubMed
概括

体蛋白Psu通过在开放状态下紧Rho环来抑制转录终结因子Rho. 这种机制揭示了一个普遍的细菌基因调节策略,涉及蛋白质寡合体状态的调节.

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