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Updated: Jun 3, 2025

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
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跨亚型的肉瘤干细胞的遗传和表观遗传特征识别了EZH2作为治疗点

Edmond O'Donnell1, Maria Muñoz2, Ryan Davis3

  • 1Department of Orthopedic Surgery, University of California Davis, Sacramento, CA, 95817, USA.

NPJ precision oncology
|January 9, 2025
PubMed
概括

软组织肉瘤癌干细胞 (STS-CSCs) 驱动了多克索鲁比辛的耐药性. 用tazemetostat针对EZH2 (增强Zeste同源2) 减少了STS-CSC种群,提供了一个潜在的治疗策略.

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