夜间排尿频率与睡眠血压之间的个人内相关性:纳加哈马研究
Yasuharu Tabara1,2, Takeshi Matsumoto3, Kimihiko Murase3
1Graduate School of Public Health, Shizuoka Graduate University of Public Health, Aoi-ku, Shizuoka, Japan. tabara@s-sph.ac.jp.
概括
夜间醒来排尿 (夜间排尿) 与睡眠血压 (BP) 的升高有关. 每一次夜间排尿都与缩和腹缩睡眠BP的增加有关.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 睡眠医学 睡眠医学
背景情况:
- 已知夜间排尿频率与睡眠血压 (BP) 有关.
- 睡眠BP随着夜间排尿的每次发作而增加的精确程度在个人中仍然不清楚.
研究的目的:
- 为了研究夜间排尿频率和睡眠血压之间的个体内关系.
- 为了确定与夜间排尿每次增加相关的睡眠BP的定量增加.
主要方法:
- 研究了一组2418名社区居民 (平均年龄为61.1岁).
- 参与者接受了一周的门诊血压监测 (ABPM),使用上臂袖子,在睡眠期间自动测量血压.
- 参与者在睡眠日记中自行记录夜间排尿的频率.
主要成果:
- 睡眠时的静缩和静缩血压显著增加,夜间排尿的频率更高.
- 具体来说,睡眠系统性血压从0到1次排尿增加了2.1 mmHg (P < 0.001),从1到2次排尿增加了1.8 mmHg (P < 0.001),从2次排尿增加到≥3次排尿增加了1.4 mmHg (P = 0.012).
- 这些关联仍然显著,并且独立于包括年龄,使用抗高血压药物,降低功能和睡眠呼吸障碍在内的因素.
结论:
- 夜间排尿的频率显示出与睡眠血压升高的一致的个体内相关性.
- 这种关系独立于基线血压和其他临床因素.
- 夜间排尿频率可以作为一个有价值的指标来识别那些可以从详细的门诊血压监测中受益的人.
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