相关实验视频

Updated: Jun 3, 2025

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

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启用CRISPR的自主可转移元件 (CREATE) 用于基于RNA的基因编辑和传递.

Yuxiao Wang1, Ruei-Zeng Lin2, Meghan Harris2

  • 1Myeloid Therapeutics Inc., Cambridge, MA, 02139, USA. ywang@myeloidtx.com.

EMBO reports
|January 9, 2025
PubMed
概括

一种名为CRISPR-Enabled Autonomous Transposable Element (CREATE) 的新基因组编辑技术允许在没有DNA断裂的情况下精确地插入基因. 这种基于RNA的系统通过有效地传递大基因,显示出治疗遗传疾病的潜力.

关键词:
这就是CRISPR/Cas9的作用.基因编辑 基因编辑基因治疗 基因治疗在反向转换中.

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