影响晚年抑郁症老年患者认知功能的危险因素:范围审查
Ping Jiang1, Yunfeng Gao1,2, Lin Wang1
1Department of Health Management Research, Chengde Medical University, Chengde, China.
Brain and behavior
|January 10, 2025
概括
认知障碍是晚年抑郁症 (LLD) 的关键症状,影响患者的生存率. 本次审查确定了影响因素和评估工具,强调了对LLD特定评估的需要.
科学领域:
- 老年精神病学是一门精神病学专业.
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
背景情况:
- 认知障碍是患有抑郁症的老年患者的一个重要症状,即使在抑郁症缓解后也会持续存在.
- 了解晚年抑郁症 (LLD) 认知障碍的影响因素对于开发预测模型和有针对性的干预至关重要.
研究的目的:
- 审查目前对LLD患者认知障碍的负面影响因素.
- 识别和评估用于LLD认知障碍评估的可用工具.
- 为制定针对LLD的有针对性的干预计划提供框架.
主要方法:
- 在2023年11月之前对6个英语和4个中文数据库进行系统范围审查.
- 两个独立研究人员对提取的数据进行了专题分析.
- 包括符合资格标准的22篇文章,包括纵向,病理控制,横截面,队列和随机控制的研究.
主要成果:
- 确定了影响因素的五个关键主题:社会人口统计学,生理学,心理学,遗传学和其他相关因素.
- 编制了19个认知功能的各种评估工具的综合清单.
- 突出了研究设计的异质性,包括纵向,病理控制,截面,队列和随机控制的研究.
结论:
- 认知功能障碍是LLD的关键症状,显著影响患者的结果.
- 对影响因素的现有研究涵盖了社会人口统计学,生理学,心理学和遗传学领域.
- 目前用于重大抑郁症的认知评估工具缺乏对LLD患者的验证可靠性和适用性.
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