对跨性别个人的基因分析:对医生态度和外科决策的影响
Duygu Onur Cura1, Ayfer Ülgenalp1,2, Tufan Çankaya2
1Department of Molecular Medicine, Institute of Health Sciences, Dokuz Eylül University, Izmir, Türkiye.
Brain and behavior
|January 10, 2025
概括
遗传分析可能会对跨性别和性别多样性 (TGD) 个体的医生态度和性别确认手术决定产生积极的影响. 然而,早期教育和社区参与对于公平获得医疗保健至关重要.
科学领域:
- 医学遗传学 医学遗传学
- 医学社会学 医学社会学
- 跨性别者健康 跨性别者健康
背景情况:
- 有限的研究存在于遗传数据对跨性别和性别多样性 (TGD) 个体的态度的影响.
- 了解医生对遗传发现的看法对于改善TGD社区获得医疗保健至关重要.
- 在TGD社区中,基因研究正在出现,需要检查它们对医疗实践的影响.
研究的目的:
- 研究遗传变化如何影响医生对TGD个体的态度.
- 评估遗传数据对医生关于性别确认手术 (GCS) 的决定的影响.
- 确定减少TGD社区面临的医疗保健不平等的战略.
主要方法:
- 在网上调查中,224名医生使用了土耳其版本的对变性人群态度 (ATTIS) 进行了在线调查.
- 使用Scheffé和最不显著差异 (LSD) 后期分析来评估医生对遗传发现对TGD个体的影响的看法.
- 多变量多项逻辑回归分析了医生在鉴定基因变异的背景下对GCS的决定.
主要成果:
- 超过三分之二的医生 (67.1%) 认为基因分析将有利于TGD个体.
- 对GCS决策积极看待与性别多样性相关的遗传改变的医生对TGD个体的整体态度较不积极 (p < 0.001).
- 年轻的医生 (≤35岁) 更有可能报告遗传发现对GCS决策的"无影响"与"积极影响" (OR=3.299,p=0.009).
结论:
- 虽然基因分析可能对医生态度和GCS决策产生积极影响,但必须权衡潜在的危害与益处.
- 医生需要早期和持续的教育,以培养对性别认同的全面理解和观点.
- 让TGD社区参与决策和制定基因数据解释的明确指南是必不可少的.
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