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Updated: Jun 3, 2025

Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells
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循环mRNA疫苗对抗SARS-COV-2变种通过可降解脂质纳米粒子启用

Ke Huang1, Na Li2, Yingwen Li2

  • 1Department of Chemical and Biological Engineering, Monash University, Clayton 3800, Victoria, Australia.

ACS applied materials & interfaces
|January 10, 2025
PubMed
概括

一种新的生物降解脂质 (AX4) 和圆形mRNA (cmRNA) 创造了一个稳定的mRNA疫苗 (cmRNA-1130),有效期为6个月. 这种疫苗显示出强大的免疫激活和疾病预防和治疗的安全性.

关键词:
在 COVID-19 疫情中,这是一个圆形的mRNA.可降解的电离性脂质可降解脂质纳米颗粒是一种纳米粒子.这是mRNA疫苗.

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