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Updated: Jun 3, 2025

Methods for the Modulation and Analysis of NF-κB-dependent Adult Neurogenesis
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Methods for the Modulation and Analysis of NF-κB-dependent Adult Neurogenesis

Published on: February 13, 2014

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开发一种合成特异性NF-κB激活的小鼠模型

McKenzie E Sup1, Adam C Abraham2, Min Kyu M Kim3

  • 1Department of Biomedical Engineering, Columbia University, New York, New York, USA.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
|January 10, 2025
PubMed
概括

研究人员开发了一种针对肠炎的新老鼠模型,这种疾病会导致关节炎症. 这种模型有助于研究疾病.

关键词:
Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1 Gli1在 NF-kB 中.凝聚力 凝聚力 凝聚力 凝聚力脑膜炎 (炎) 是一个病.过度使用过度使用.牛皮关节炎 牛皮关节炎脊柱性关节炎 (spondyloarthritis) 是一个疾病.

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NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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