基于voxel的形态测量和子场体积测量分析显示,边缘系统参与了耳
Sekwang Lee1, Sung-Bom Pyun1,2, Youngbo Sim3
1Department of Physical Medicine and Rehabilitation, Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
概括
脑部成像显示,与对照组相比, tinnitus 患者的杏仁核和海马体积更大. 这些发现突显了边缘系统在声中的作用,并可能改善神经疾病的诊断.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 精神病学是一个精神病学.
背景情况:
- 耳,其特点是没有外部来源的感知声音,尚未完全理解.
- 新出现的证据表明,涉及非听觉大脑结构,特别是边缘系统.
研究的目的:
- 为了比较 tinnitus 患者和对照者之间的大脑结构体积.
- 为了研究边缘系统在声中的作用.
主要方法:
- 使用基于voxel的形态测量和子场体积测量.
- 分析了53名耳患者和52名对照者的大脑结构 (杏仁体,海马体,丘脑).
主要成果:
- 耳患者表现出较大的杏仁体体积 (整体,基底核,右侧,左侧) 和海马子场体积 (体头,左侧体,左前体头).
- 在thalamic体积中没有观察到任何显著差异.
- 在耳组中,观察到质体,杏仁体和海马体的灰质体积增加,以及特定带膜和顶膜区域的皮质厚度变化.
结论:
- 研究结果支持边缘系统在声中的参与.
- 子场体积学可以帮助识别神经和精神疾病中的结构差异.
相关概念视频
Hearing
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
The Cochlea
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
Perception of Sound Waves
The human ear is not equally sensitive to all frequencies in the audible range. It may perceive sound waves with the same pressure but different frequencies as having different loudness. Moreover, the perception of sound waves depends on the health of an individual's ears, which decays with age. The health of one's ears may also be affected by regular exposure to loud noises.
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same frequency...
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same frequency...
The Auditory Ossicles
The auditory ossicles of the middle ear transmit sounds from the air as vibrations to the fluid-filled cochlea. The auditory ossicles consist of two malleus (hammer) bones, two incus (anvil) bones, and two stapes (stirrups), one on each side. These bones develop during the fetal stage and are the ones to ossify first. They are fully mature at birth and do not grow afterward.
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
Anatomy of the Ear
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
Perceiving Loudness, Pitch, and Location
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...


