药物使用和左侧门置换在感染性内心炎患者的结果
Katie J Hogan1,2,3, Christopher B Sylvester1,2, Travis J Miles1
1Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
Annals of thoracic surgery short reports
|January 10, 2025
概括
由于与物质使用相关的传染性内心炎 (SU-IE) 进行门手术的患者年龄较小,但承担更高的费用和更多的再入院. 改善退院和再接收预防策略对于SU-IE患者至关重要.
科学领域:
- 心血管外科心血管外科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 增加的物质使用 (SU) 率需要增加左侧门手术,以治疗与SU相关的传染性内心炎 (SU-IE).
- 对接受门置换的SU-IE和非SU-IE患者之间的结局的比较分析至关重要.
研究的目的:
- 为了比较SU-IE患者和没有SU的感染性内心炎 (IE) 患者之间的结果,再入院和医疗费用.
- 确定影响IE患者住院死亡率和再入院率的因素.
主要方法:
- 利用全国再接收数据库 (2016-2018) 对一组10098名接受隔离性大动脉或心心置换的患者进行了研究.
- 使用多变量后勤回归和卡普兰-梅尔分析与Cox比例危险模型来评估死亡率和再接收风险.
主要成果:
- SU-IE患者 (21%) 较年轻 (38岁与60岁相比),并发症较少,但住院时间较长,费用较高.
- SU-IE患者在住院死亡率较低 (3.0%对5.8%),但在再入院后死亡率较高 (9.6%对4.6%).
- 在 SU-IE 患者中,每日历年再入院率显著高 (35.1%对31.0%).
结论:
- 尽管年龄较小,并较少的并发症,SU-IE患者消耗更多的资源,经历更多的日历年再入院.
- 需要有效的策略来优化出院计划,并降低SU-IE患者的再入院率.
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