功能与心脏手术后住院患者死亡率和发病率的关联
Vikram Fielding-Singh1, Matthew W Vanneman1, Tracey Hong1
1Division of Cardiovascular and Thoracic Anesthesia, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California.
Annals of thoracic surgery short reports
|January 10, 2025
概括
晚期慢性病 (CKD) 与更多的心脏手术和更高的住院死亡率有关. 这项研究强调了接受心脏手术的CKD患者的风险增加.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 目前关于非透析性慢性病 (CKD) 患者的心脏手术率和结果的数据有限.
- 了解CKD阶段和术后结果之间的关系对于患者护理至关重要.
研究的目的:
- 为了检查心脏外科手术在病不同阶段的发生率.
- 评估慢性病 (CKD) 阶段与心脏手术后住院死亡率之间的关联.
主要方法:
- 在美国 (2010-2019年) 对心脏外科手术的成人入院病例的分析.
- 病被分类为CKD G3阶段,CKD G4/G5阶段和末期病 (ESKD).
- 多变量逻辑回归用于评估CKD阶段与住院死亡率之间的关联.
主要成果:
- 估计有2,772,081个心脏外科手术程序被确定.
- 患有CKD,特别是ESKD的患者中,手术发生率更高 (1000人年中有13.0人).
- 住院死亡率随着CKD严重程度的增加:3.7% (CKD G3),6.7% (CKD G4/G5) 和8.8% (ESKD),与正常功能2.2%相比.
结论:
- 晚期CKD与美国心脏外科手术发生率的增加有关.
- 接受心脏手术的CKD患者面临着显著更高的住院死亡风险.
- 这些发现强调了对CKD患者风险分层和风险管理的重要性.
相关概念视频
Heart Failure Drugs: Diuretics
338
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
338
Factors Affecting Renal Clearance: Renal Impairment
53
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
53
Kidney Structure
68.7K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
68.7K


