未经治疗的头部和部状细胞癌患者的结果和预后因素
Hisashi Kessoku1, Yosuke Mizunari1
1Department of Otorhinolaryngology, Jikei University Kashiwa Hospital, Kashiwa, JPN.
Cureus
|January 10, 2025
概括
未经治疗的头部和部状细胞癌患者的预后不佳,平均存活时间为20.5周. 晚期的第四阶段疾病和缺乏社会支持显著恶化了这些患者的结果.
科学领域:
- 在瘤学瘤学.
- 头部和部癌症研究研究
背景情况:
- 关于未经治疗的头部和部状细胞癌 (HNSCC) 的预后和死亡风险因素的数据有限.
- 了解这一群体的结果对于明智的临床决策和患者咨询至关重要.
研究的目的:
- 为了确定没有接受治疗的HNSCC患者的结果.
- 调查未经治疗的HNSCC病例中与预后和死亡率相关的因素.
主要方法:
- 对来自日本单一机构的43名未经治疗的HNSCC患者 (2015-2021) 的回顾性分析.
- 收集关于患者人口统计,不治疗原因,临床阶段和生存时间的数据.
主要成果:
- 患者的平均年龄为79岁;男性占主导地位.
- 不接受治疗的主要原因包括患者拒绝,痴呆和晚年.
- 平均存活时间为20.5周,一年内死亡率为90%. 晚期IV期疾病是主要的生存决定因素.
- 对于第四阶段的患者,独自生活或没有家庭支持预测预后不佳.
结论:
- 未经治疗的HNSCC具有显著的死亡风险,平均存活时间约为五个月.
- 医疗保健提供者应该意识到这些可怕的后果,以便更好地告知患者治疗选择.
- 社会支持是影响高级未经治疗的HNSCC生存的关键因素.
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