斯瓦恩维尔-IV片的安全性研究和组合分析,特别提及其在SARS-CoV-2治疗中的治疗效用
K Ramachandra Reddy1, Priya Kumari1, K Vinay2
1Department of Rasa Shastra (Ayurvedic Pharmaceutics) Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi, IND.
Cureus
|January 10, 2025
概括
阿育吠陀药物Svarnvir-IV显示了对COVID-19的安全性和有效性. 在Drosophila的体内研究证实了其安全性,支持其用于管理SARS-CoV-2变种.
科学领域:
- 艾尔韦达医学是一种医药.
- 药理学 药理学是指药理学的学科.
- 病毒学 病毒学
背景情况:
- 传统的阿育吠陀草药和矿物质配方在治疗COVID-19方面显示出有前途.
- 斯瓦恩维尔-IV片在体外表现出对SARS-CoV-2的杀毒活性及其治疗作用.
- 之前的基于细胞的测定证实了Svartnvir-IV在细胞毒性方面的安全性.
研究的目的:
- 为了评估Svartnvir-IV片的体内安全性.
- 进行Svartnvir-IV片的组成分析.
- 评估Svartnvir-IV在潜在的COVID-19管理中的整体安全性和有效性.
主要方法:
- 在体内用Drosophila melanogaster及其幼虫进行药物查.
- 通过原子吸收光谱 (AAS),感应合等离子体质谱 (ICP-MS) 和扫描电子显微镜-能量分散光谱 (SEM-EDS) 进行元素组成分析.
- 使用X射线衍射 (XRD) 和SEM进行微结构检查.
主要成果:
- 斯瓦恩维尔-IV片在多索菲拉菌中被证明是安全的,剂量高达1mg/ml.
- 与对照人群相比,没有观察到对形态,生理或昼夜活动模式的不良影响.
- 元素和微观结构分析提供了全面的药片组成概况.
结论:
- 斯瓦恩维尔-IV片表现出良好的体内安全概况.
- 组合分析证实了阿育吠陀配方的完整性和特征.
- 这些发现支持Svartnvir-IV的发展,作为对SARS-CoV-2变种的可访问和安全的治疗选择.
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