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Updated: Jun 3, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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通过序列催化方式对非融合的八个成员O-异环进行反选择性合成

Suo-Suo Qi1, Xiao-Ping Sun1, Yan-Biao Sun1

  • 1Catalytic Hydrogenation Research Center, State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Key Laboratory of Green Pesticides and Cleaner Production Technology of Zhejiang Province, Zhejiang University of Technology, Hangzhou 310014, P. R. China.

Organic letters
|January 10, 2025
PubMed
概括

一种新的性双功能方胺/DBU催化剂使八个成员的O-异环的酶选择性合成成为可能. 这种方法涉及不对称的加法和区域选择性循环,可以精确控制立体化学.

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