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Updated: Jun 3, 2025

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在基因工程小鼠中模拟恶性间皮瘤.

Yuwaraj Kadariya1, Eleonora Sementino1, Xiang Hua2

  • 1Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.

Current protocols
|January 10, 2025
PubMed
概括

间皮瘤研究进展,基因工程小鼠模型 (GEMMs) 模仿人类疾病,帮助开发新的癌症疗法和预防策略.

关键词:
石棉的致癌性 石棉的致癌性有条件的淘汰赛小鼠.内内瘤的发生内内瘤的发生半质瘤 (Mesothelioma) 是一种中质瘤.

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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