长时间的卵巢刺激不会在新鲜胚胎移植后恶化新生儿结果
1Reproductive Medicine Center, Department of Obstetrics and Gynecology, Tang Du Hospital, Air Force Medical University, Xi'an, China.
BJOG : an international journal of obstetrics and gynaecology
|January 10, 2025
概括
在接受新生胚胎移植 (fET) 的女性中,长时间的卵巢刺激不会显著影响新生儿的结果. 这项研究发现,通过自身体外受精 (IVF) 怀孕的单体新生儿没有增加不良事件的风险.
科学领域:
- 生殖医学 生殖医学
- 新生儿健康 新生儿健康
- 在体外受精中进行体外受精.
背景情况:
- 卵巢刺激方案在辅助生殖技术中至关重要.
- 卵巢刺激的持续时间可能会影响怀孕和新生儿的结果.
- 了解这些关系对于优化试管婴儿成功和婴儿福祉至关重要.
研究的目的:
- 调查长时间的卵巢刺激与新生儿结局之间的关联.
- 为了确定延长刺激期是否会影响出生体重,妊娠年龄或其他新生儿参数.
- 为了评估自主新生胚胎移植 (FET) 后单体新生儿的风险.
主要方法:
- 追溯队列研究涉及3529名接受自主试管婴儿治疗的患者.
- 2016年8月至2022年12月期间从大学附属中心收集的数据.
- 采用了单变量,多变量回归和倾向得分匹配 (PSM) 分析.
主要成果:
- 在刺激持续时间和出生体重或妊娠年龄之间没有发现显著的关联.
- 分类分析没有显示出低出生体重,巨,SGA,LGA或早产的风险增加.
- 倾向性得分匹配证实了这些发现,表明没有新生儿不良影响.
结论:
- 长时间的卵巢刺激似乎与单个婴儿的新生儿不良结果无关.
- 卵巢刺激的持续时间不太可能对通过自主FET怀孕的新生儿构成风险.
- 目前的发现支持当前的试管婴儿实践,关于刺激持续时间和新生儿健康.
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