吸烟史和尼古丁依赖改变了阻断性睡眠呼吸暂停-呼吸暂停综合征患者的睡眠特征
Ioanna Grigoriou1, Serafeim-Chrysovalantis Kotoulas2, Konstantinos Porpodis3
1Respiratory Failure Clinic and Sleep Laboratory, General Hospital of Thessaloniki "G. Papanikolaou", Aristotle's University of Thessaloniki, 541 24 Thessaloniki, Greece.
Healthcare (Basel, Switzerland)
|January 10, 2025
概括
吸烟史,以包年来衡量,显著影响阻塞性睡眠呼吸暂停-呼吸暂停综合征 (OSAHS) 的严重程度和特征. 尼古丁依赖与不正常的睡眠行为 (如不安睡眠) 更密切相关.
科学领域:
- 肺部病理学 肺部病理学
- 睡眠医学 睡眠医学
- 成研究 研究成研究
背景情况:
- 吸烟和睡眠之间的复杂关系,特别是关于阻塞性睡眠呼吸暂停-睡眠暂停综合征 (OSAHS),仍然不完全理解.
- 调查吸烟史和尼古丁依赖对OSAHS的具体影响对于全面的患者护理至关重要.
研究的目的:
- 检查吸烟史 (包年) 和尼古丁依赖 (法格斯特罗姆尺度) 与流行病学和睡眠相关变量之间的相关性,在怀疑OSAHS的吸烟者队列中.
- 阐明吸烟年龄和尼古丁依赖如何影响OSAHS诊断,严重程度和相关睡眠障碍.
主要方法:
- 一项横截面研究包括2359名目前或前吸烟者,他们在13年内参加了睡眠诊所.
- 收集的数据包括吸烟史 (包年),尼古丁依赖 (法格斯特罗姆尺度),以及各种睡眠研究参数 (例如,AHI,ODI,SaO2,ESS).
- 统计分析将吸烟变量与并发症,OSAHS严重程度和睡眠行为相关联.
主要成果:
- 较大的吸烟史 (包年) 与增加的OSAHS严重程度有关,包括更高的呼吸暂停-呼吸暂停指数 (AHI),氧气不和指数 (ODI) 和更长的呼吸暂停持续时间.
- 增加的包年与更高的爱普沃思睡眠度量 (ESS) 评分和改变的REM睡眠相关.
- 更高的尼古丁依赖与异常的睡眠运动和不安的睡眠有显著的联系.
结论:
- 吸烟史,按包年量化,似乎显著影响阻塞性睡眠呼吸暂停-呼吸暂停综合征的特征和严重程度.
- 尼古丁依赖与异常的睡眠行为相比,与核心OSAHS指标相比,与尼古丁依赖与异常的睡眠行为更为密切相关.
- 这些发现凸显了OSAHS患者吸烟数量与依赖睡眠健康的明显影响.
更多相关视频
相关概念视频
Sleep Apnea
126
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
126
Substance Use Disorders Affecting Sleep
158
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
158
Insufficient Sleep and Sleep Deprivation
132
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
132
Chronic Obstructive Pulmonary Disease
1.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.2K
Other Pulmonary Disorders
801
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
801
Sleep-Wake Cycles
1.2K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.2K


