帕金森病主观认知和社会功能在COVID-19大流行之前和期间的变化
Nishaat Mukadam1, Shraddha B Kinger1, Sandy Neargarder1,2
1Department of Psychological and Brain Sciences, Boston University, 900 Commonwealth Ave., 2nd Floor, Boston, MA 02215, USA.
Healthcare (Basel, Switzerland)
|January 10, 2025
概括
COVID-19大流行对帕金森病 (PwPD) 患者的主观认知和社会功能产生了负面影响. 这些下降与增加的焦虑,疲劳,运动症状和抑郁症有关.
科学领域:
- 神经学 神经学
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 随着COVID-19的流行和相关的社会隔离,可能会对帕金森病患者 (PwPD) 的生活质量产生负面影响.
- 疫情对PwPD患者的主观认知和社会功能的具体影响尚不清楚.
研究的目的:
- 纵向分析PwPD在COVID-19大流行之前和期间主观认知和社会功能中的变化.
- 了解这些变化与其他健康因素之间的关系.
主要方法:
- 一项纵向研究比较PwPD在COVID-19大流行之前 (2017-2019) 和期间 (2021).
- 使用了在线调查和问卷,包括Neuro-QoL,贝克抑郁 inventory-II,帕金森氏症焦虑量表,MDS-UPDRS和冠状病毒影响量表.
主要成果:
- 主观认知和社会功能下降与增加的焦虑,疲劳和运动症状相关.
- 主观认知能力下降也与抑郁症和社会功能下降有关.
- 女性报告COVID-19的影响更大;在男性中,个人COVID-19经历与认知能力下降相关.
结论:
- 在PwPD中,主观认知和社会功能与各种运动和非运动症状复杂相关.
- 这些发现对开发针对性治疗疫情影响的PwPD有重大影响.
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