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A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
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超越B细胞血液恶性瘤的CAR-T疗法

Martina Canichella1, Paolo de Fabritiis1,2

  • 1Hematology, St. Eugenio Hospital, ASL Roma2, 00144 Rome, Italy.

Cells
|January 10, 2025
PubMed
概括

化学抗原受体T细胞 (CAR-T) 疗法显示出超越B细胞癌症的前景,扩展到新的血液和非血液疾病. 正在开发分子工程策略,以克服目前对更广泛的CAR-T细胞应用的局限性.

关键词:
在血液学中的CAR-T.在固体瘤中CAR-T.传染病和自身免疫性疾病.瘤免疫抑制可以抑制免疫.瘤微环境是一个微环境.

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