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在医疗辅助生殖中怀孕期间和之后的心理健康:丹麦队列研究

Marie Mulvad Grønlund¹, Line Riis Jølving², Sören Möller¹

¹Research Unit OPEN, Department of Clinical Research, University of Southern Denmark, JP Winsløw Vej 21, Odense, DK - 5000, Denmark.

Archives of women's mental health

|January 10, 2025

概括

接受生育治疗的女性与自然怀孕的女性相比,没有经历更高的产前压力或产后抑郁症. 医疗辅助生殖方法没有影响这些心理健康结果.

科学领域:

生殖医学生殖医学
围产期心理健康围产期心理健康
心理社会妇产科心理社会妇产科

背景情况:

医疗辅助生殖 (MAR) 越来越多地用于不孕症,引发了对女性潜在心理健康影响的担忧.
了解生育治疗与母亲精神健康之间的关系对于提供足够的支持至关重要.

研究的目的:

调查生育治疗,包括特定的方法 (体内/体外),是否与怀孕期间或怀孕后的精神健康受损有关.
为了比较通过生育治疗怀孕的女性与自发受孕的女性的产前压力和产后抑郁症状.

主要方法:

利用来自Odense儿童队伍的自我报告数据,评估产前压力 (PSS-10) 和产后抑郁症状 (EPDS).
采用线性回归用于压力评分和逻辑回归用于抑郁症状,比较受孕治疗的妇女与自发怀孕的妇女.
基于整体生育治疗使用和特定的MAR方法 (体内/体外) 分析的数据.

主要成果:

通过生育治疗怀孕的妇女 (平均PSS-10:11.38) 和自发怀孕的妇女 (平均PSS-10:11.78) 之间没有发现产前压力水平的显著差异.
产后抑郁症状 (EPDS评分≥11) 在两组中均有相似的患病率 (9.7%对10.7%).
特定的医疗辅助生殖方法 (体内或体外) 没有影响产前压力或产后抑郁症状.

结论:

与自发怀孕妇女相比,在受精治疗后分娩的妇女没有报告高水平的产前压力或产后抑郁症状.
目前的研究结果表明,医疗辅助生殖,无论方法如何,都与围产期的心理健康负担增加无关.

关键词:

这是EPDS的EPDS.不孕不育不孕不育不孕不育医疗辅助生殖是一种医疗辅助生殖.心理健康心理健康在 PSS-10 中使用.

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