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Updated: Jun 3, 2025

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
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转基托酶通过调节R循环形成来减弱质瘤细胞的化疗敏感性

Minjie Fu1, Mengli Zhang1, Licheng Zhang1

  • 1Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China; National Center for Neurological Disorders, Shanghai 200040, China; Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai 200040, China; Neurosurgical Institute of Fudan University, Shanghai 200040, China; Shanghai Clinical Medical Center of Neurosurgery, Shanghai 200040, China.

Cell reports
|January 10, 2025
PubMed
概括

转基因酶 (TKT) 蛋白质,而不是其代谢活性,通过调节核R循环来增加质母细胞瘤化学抵抗. 降低TKT水平可以提高化疗对抗脑瘤的有效性.

关键词:
CP: 癌症 癌症 癌症在R-Loop中使用.TKT TKT 在这里.化疗敏感性 化疗敏感性质瘤 质瘤 是一种

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