概括
胸腔转移在差异化甲状腺癌 (DTC) 中是罕见的. 缺乏放射性 (131I) 激情,放射性耐火性DTC和显著的恶性肺溢出预测这些患者的存活率很低.
科学领域:
- 在瘤学瘤学.
- 核医学就是核医学.
- 胸部外科手术 胸部外科手术
背景情况:
- 从差异化甲状腺癌 (DTC) 引起的多性转移 (PM) 是不常见的.
- 关于DTC与PM的特征和预后的临床数据有限.
- 放射性 (131I) 治疗是DTC转移和复发的标准治疗方法.
研究的目的:
- 调查DTC和PM患者的临床病理特征.
- 评估长期预后,并确定DTC和PM患者的预后因素.
- 评估手术和131I治疗在治疗PM的DTC治疗中的有效性.
主要方法:
- 2010-2023年上海第六人民医院的医疗记录的回顾性审查.
- 在14473名DTC患者中,确定了27名DTC和PM患者.
- 使用Kaplan-Meier方法进行整体生存 (OS) 分析.
主要成果:
- 在DTC中PM的患病率为1.87‰.
- 与5年后更糟糕的生存状况相关的因素包括超过中度的恶性多流液 (MPE),缺乏131I狂热度和耐放射性的DTC (RR-DTC).
- 在随访时,44.44%的患者死亡,没有观察到完全反应.
结论:
- 胸腔转移是一种罕见但显著的DTC并发症.
- 超过中度的MPE,缺乏131I贪和RR-DTC是PM的DTC患者的不良预后指标.
- 需要进一步的研究来优化PM的DTC的治疗策略.
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