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Léonore Flipo1, Frédéric Coppin1, L Garcia-Sanchez1

  • 1Institut de Radioprotection et de Sûreté Nucléaire (IRSN), PSE-ENV/STAAR/LRTA, PSE-ENV/SPDR/LT2S, Saint-Paul-lez-Durance, F-13115, France.

概括

动力模型比平衡模型更准确地预测河流中的放射性核酸转移,特别是当环境条件发生变化时. 这些模型更好地捕捉了诸如和等污染物的复杂固体/液体分离.

相关概念视频

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Methods for Studying Drug Absorption: In situ

In situ experiments, such as the Doluisio method and Single-Pass Perfusion technique, provide critical insights into drug uptake by simulating in vivo conditions for drug absorption.
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Typical Model Studies01:30

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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

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Physiological Pharmacokinetic Models: Assumption with Protein Binding01:13

Physiological Pharmacokinetic Models: Assumption with Protein Binding

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Pharmacokinetic Models: Comparison and Selection Criterion01:26

Pharmacokinetic Models: Comparison and Selection Criterion

Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.
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One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

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On...
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