贝塞斯达系统报告甲状腺细胞病理学:儿童甲状腺结节中恶性瘤的风险
Sabrina de Los Angeles Pintos1, Florencia Varela2, Ana Jaén3
1Division of Pediatric Surgery, Hospital Italiano de Buenos Aires, Argentina.
Journal of pediatric surgery
|January 10, 2025
概括
儿童的甲状腺结节具有更高的恶性瘤风险. 这项研究发现,儿童甲状腺结节中贝塞斯达类II,IV,V和VI恶性瘤的风险与更新的指导方针一致,为管理策略提供了信息.
科学领域:
- 内分泌学 在内分泌学.
- 儿科瘤学 儿科瘤学
- 细胞病理学 细胞病理学
背景情况:
- 甲状腺结节在儿童中不常见,但患恶性瘤的几率较高.
- 贝塞斯达甲状腺细胞病理报告系统 (TBSRTC) 有助于评估甲状腺结节恶性瘤风险.
- 2023年TBSRTC更新包括儿科特异性风险预测和管理指南.
研究的目的:
- 评估儿童群体中每个贝塞斯达 (BT) 类别的恶性瘤 (ROM) 风险.
- 将观察到的ROM与2023年TBSRTC儿科特定预测进行比较.
主要方法:
- 从2008年到2023年进行细针吸收 (FNA) 的儿科患者的回顾性队列研究.
- 通过将贝塞斯达类别与手术组织学或长期随访进行比较来确定ROM.
- 观察到的ROM与2023年TBSRTC数据进行了比较,使用了95%的置信区间 (CI).
主要成果:
- 165名患有甲状腺结节的儿科患者接受了FNA;110人被纳入分析.
- 恶性瘤的发生率为BT II的10.5%,BT IV的42.8%,BT V的87.5%,BT VI的100% .
- 观察到的ROM与所有类别的2023年TBSRTC儿科人口数据一致.
结论:
- 对于BT II,IV,V和VI的儿科甲状腺结节ROM比成人TBSRTC数据高,但与2023年儿科TBSRTC数据相似.
- 更新的儿科专用指南对于完善甲状腺结节儿童的随访和治疗方案至关重要.
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