定制质活检:基于瘤大小的最佳核心数量和位置,以提高诊断准确度 - - 一项前性的活体研究
Navid Masoumi1, Milad Fooladgar2, Atoosa Gharib3
1Department of Urology, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Urology and Nephrology Research Center, Research Institute for Urology and Nephrology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Urology
|January 10, 2025
概括
最佳的质活检策略取决于大小. 对于≤7厘米的质量,最好做三次外围活检或两次中央活检. 对于较大的质量 (>7厘米),四次外围活检或两次中心活检的准确性更高.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 病理学 病理学 病理学
- 在瘤学瘤学.
背景情况:
- 质需要准确的诊断.
- 活检策略旨在最大限度地提高诊断产量.
- 质量大小会影响诊断的准确性.
研究的目的:
- 确定活检核心的最佳数量和位置.
- 最大限度地提高质活检的诊断准确度.
- 与脏质量大小相关联活检策略.
主要方法:
- 360名患有质的患者的观察性研究.
- 在切割后进行的ex-vivo核心针活检.
- 活检的数量 (1-4) 和位置 (外围/中央) 不同.
- 将活检结果与永久性组织病理学结果进行比较.
主要成果:
- 对于质量≤7厘米 (T1a,T1b),三个外围或两个中心活检是最准确的.
- 对于质量>7厘米 (T2a,T2b),四个外围或两个中心活检是最准确的.
- 组织学特征没有显著影响诊断准确性.
结论:
- 对于≤7厘米的质量,三个外围或两个中心活检核最大限度地提高了诊断准确度.
- 对于大于7厘米的质量,四个外围或两个中心活检核提供了最高的诊断准确性.
- 活检策略应根据质量大小进行调整.
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