使SMAD4,JOSD2

Jiamin Du1, Jiao Wang1, Fujing Ge1

  • 1Institute of Pharmacology & Toxicology Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China.

Biochemical pharmacology
|January 10, 2025
PubMed
概括

含有2 (JOSD2) 的duebiquitinase josephin域通过稳定SMAD4促进乳腺癌转移. 抑制JOSD2为转移性乳腺癌提供了潜在的治疗策略.

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