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克森63与Preserflo MicroShunt植入物在患有初级开角玻璃眼病的患者中
José María Martínez-de-la-Casa1, Antonio Pascual-Santiago2, Laura Morales-Fernandez2
1Department of Ophthalmology and ORL, Faculty of Medicine, Clinico San Carlos Hospital, Complutense University, Clinico San Carlos Hospital Health Research Institute (IdISSC), Calle del Prof Martín Lagos, s/n,, Madrid, 28040, Spain. jmmartinezcasa@gmail.com.
Scientific reports
|January 10, 2025
概括
无论是Xen 63还是Preserflo MicroShunt设备都有效地降低了初级开角玻璃眼 (POAG) 患者的眼内压力 (IOP). 12个月后,这两种植入物在减少IOP和药物需求方面表现出可比的安全性和有效性.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 手术设备 手术设备
背景情况:
- 主要开角青光眼 (POAG) 是全球不可逆转失明的主要原因.
- 有效的眼内压力 (IOP) 管理对于减缓青光眼的进展至关重要.
- 最少侵入性玻璃眼手术 (MIGS) 为传统治疗提供了替代方案.
研究的目的:
- 为了比较独立的Xen 63和Preserflo MicroShunt设备在未经医疗控制的POAG患者的疗效和安全性.
- 评估在植入后12个月内IOP和眼睛潜在药物负担的减少.
- 评估两种设备的安全性,包括不良事件和干预措施.
主要方法:
- 对连续患有POAG的患者进行了回顾性,单中心的研究.
- 纳入标准:医学上不受控制的POAG,独立的Xen 63或Preserflo植入,以及12个月的随访.
- 主要结局:12个月的平均IOP. 二次结果:药物使用和安全事件.
主要成果:
- 分析了60只眼睛 (每组30只).
- 克森63和普雷塞弗洛都显著降低了手术前的内血压 (p < 0.0001) 和药物使用 (p < 0.0001),而没有显著的组间差异.
- 在Preserflo组中,一只眼睛 (3.3%) 需要移除装置;在Xen 63组中,三只眼睛 (10.0%) 需要针刺.
结论:
- 独立的Xen 63和Preserflo MicroShunt设备对于管理POAG的有效和安全.
- 这两种设备在12个月后实现了可比的IOP降低和降低药物依赖.
- 安全性概况有利,严重并发症的发生率低,需要进行干预.
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