一项前性多站点研究,评估加拿大口服液基艾滋病毒自我测试的性能和可用性
Richard A Galli1, Darshanand Maraj1, Kristin McBain1
1MAP Centre for Urban Health Solutions, Unity Health Toronto, Toronto, ON, Canada.
BMC public health
|January 10, 2025
概括
基于口服液的艾滋病毒自我测试对加拿大人来说是准确且易于使用的. 提供这些测试与基于血液的选择一起,可以提高艾滋病毒测试率,并达到更多未被诊断的个人.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 诊断测试 诊断测试 诊断测试
背景情况:
- 艾滋病毒自我检测对于识别未被诊断的个体至关重要.
- 口服液和基于血液的测试是艾滋病毒宣传的关键策略.
- 评估新的自我检测方法对于公共卫生倡议至关重要.
研究的目的:
- 评估OraQuick®艾滋病毒自我测试 (HIV-ST) 与实验室标准的性能.
- 为了确定非专业人士是否能够准确地执行和解释HIV-ST.
- 评估用户对HIV-ST产品标签的理解.
主要方法:
- 在加拿大社区卫生中心对成年艾滋病毒自我测试用户的前性研究 (2022年6月至2024年1月).
- 将HIV-ST结果与Abbott AlinityHIV抗原/抗体组合测试"黄金标准"进行比较.
- 描述性统计分析了关键测试步骤的可用性和结果解释.
主要成果:
- 负百分比的一致性是100% (95% CI: 99.9-100%) 与比较方法.
- 报告的高可用性:关键步骤的成功率为94.1%,97%的人发现指令很容易.
- 对人工结果的解释显示,平均正确解释率在59-97%之间.
结论:
- 基于口服液的HIV-ST是加拿大的准确,用户友好和不那么侵入性的HIV检测替代方案.
- 添加口腔液体自我测试补充了基于血液的选择,可能会增加艾滋病毒检测的吸收率.
- 增加自我测试设备的选择可以帮助接触未被诊断的人群,并提高整体艾滋病毒检测率.
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